ebola epidemiological triangle

3 0 obj Ebola health update:north Kivu/Ituri, DRC, 2018-2020. A "mysterious" disease began silently spreading in a small village in Guinea on 26 December 2013 but was not identified as Ebola until 21 March 2014. Jul 2020 [internet publication]. The Ebola virus disease is an epidemic that has returned to claim more lives than one can count. Ebola virus disease in West Africa: the first 9 months of the epidemic and forward projections. 2004 Jan;10(1):40-7. https://wwwnc.cdc.gov/eid/article/10/01/03-0125_article, http://www.ncbi.nlm.nih.gov/pubmed/15078595?tool=bestpractice.com. Lever, Mark S. The https:// ensures that you are connecting to the Epidemiological Triangle The agent factors of the disease include five genus viruses, Zaire Ebola virus, Bundibugyo Ebola virus, Sudan Ebola virus, Reston Ebola virus, and Tai Forest Ebola virus (Kaur, Sachdeva, Jha, & Sulania, 2017). Healthcare workers, family, and friends in close contact with the diseased are at the highest risk of getting infected, due to close contact with blood or other bodily fluids. Although the virus is not transmitted via food or water, and the proper cooking of foods should inactivate infectious particles, ingestion of contaminated food may represent a possible route of exposure in natural infections. Complete each fillable area. Since discovered, there have been known cases in Africa. Clin Microbiol Infect. https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease, 2014-2016: the worlds largest outbreak started in the DRC in 2014 and finished in 2016, with over 28,000 cases and 11,000 deaths (case fatality rate 46%). How can Ebola virus disease be prevented? 4 0 obj [25]Peterson AT, Bauer JT, Mills JN. On March 23, the WHOs Regional Office for Africa (AFRO) released the first Ebola report on the emergence of the disease in Guinea. There has been an acute worry roaming about the United States concerning the Ebola Outbreak. Nobody had any. Training for outbreak response through the Global Outbreak Alert and Response Network. They cause severe, frequently fatal, hemorrhagic fever. It can help your students understand infectious diseases and how they spread. Care of people with Ebola is difficult and varied due to the highly infectious and often fatal nature of the disease. The number cases for this current year so far is 9,936; 4,877 have been killed by this disease. https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease Thankfully, the US does not have to go through the effects of living in an Ebola epidemic because of the certain precautions taken when a case arise and the steps taken further for primary and secondary prevention. Of all cases and deaths resulting from the disease, 99.8% occurred in three neighbouring West African countries - Liberia, Sierra Leone and Guinea (WHO, 2014). FOIA With the current outbreak, this ratio has dramatically decreased as a result of scientific research leading to early detection, but the current infected population is more than 20 times the amount of any previous outbreak and this number continues to grow as no vaccine exists to prevent the disease. In this study, the new epidemiological features and prevalence trends for EVD in Guinea, Liberia, and Sierra Leone are described. Ebola virus disease in West Africa: the first 9 months of the epidemic and forward projections. The paper summarizes available evidence regarding the determinants of spread of Ebola virus disease, including health care and community related risk factors. Unfortunately, this is not the case in Africa. News-Medical. It . https://www.who.int/publications/m/item/who-recommended-criteria-for-declaring-the-end-of-the-ebola-virus-disease-outbreak. With a case fatality rate from about 50% to 90%, and the absence of preventative or curative therapies, the Ebola epidemic has led to overall global alarm and further elucidated existing global health disparities that perpetuated the epidemic with these West African countries. Fill out the Epidemiological Triangle for the current Ebola outbreak. Total loading time: 0 This virus was all the more deadly as it often took hours for any symptoms to occur. Unauthorized use of these marks is strictly prohibited. Non-human primates represent a source of infection for humans, but they are considered an accidental host (akin to humans) and not a reservoir of infection. Avoid contact with bats and nonhuman primates or blood, fluids and raw meat prepared from these animals (bushmeat) or meat from an unknown source. Although Ebola caught the worlds attention during the 1995 outbreak in Zaire, the first outbreak occurred in 1976. * A suspected case (evaluated by a clinician) or person who died from suspected EVD and had an epidemiological link to a confirmed case (but was not tested and did not have laboratory confirmation of the disease) becomes PROBABLE. Organize key facts from your research by agent, host and environment. [29]World Health Organization. This is the first FDA-approved vaccine for Ebola virus disease caused by one strain of the Ebola virus (species Zaire ebolavirus). <> May 2021 [internet publication]. 2012 Dec 28;7(12):e52986. The disease was then contained, however sporadic outbreaks of the Zaire and Sudan Ebola subtypes have risen in the Democratic Republic of the Congo, Gabon, Uganda, and Sudan; one of the latest outbreaks was in the Democratic Republic of the Congo in September of 2007. Back to basics in COVID-19: Antigens and antibodies-Completing the puzzle. The site is secure. A cross border surveillance program began in June to limit the spread of the disease between the countries. [4]Leroy EM, Gonzalez JP, Baize S. Ebola and Marburg haemorrhagic fever viruses: major scientific advances, but a relatively minor public health threat for Africa. UK Health Security Agency: ebola and Marburg haemorrhagic fevers - outbreaks and case locations. TheZaire ebolavirus has a reported case fatality rate of up to 90% in previous outbreaks. 2017 Jun 22;12(6):e0179356. Peterson AT, Bauer JT, Mills JN. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON398. 4 0 obj https://www.cdc.gov/amd/stories/ebola.html. No additional confirmed or probable cases were identified, and the outbreak was declared over on September 27, 2022. Ebola virus disease Democratic Republic of the Congo. 2022 Oct 4;22(1):769. doi: 10.1186/s12879-022-07723-6. This could explain the sporadic nature of infection and periodical outbreaks of this disease in Africa. Viral RNA and even infectious particles have been found in the genital secretions, semen, urine, saliva, feces, vomit, and in the skin of infected patients. 2011 Jul;17(7):964-76. https://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2011.03535.x/full, http://www.ncbi.nlm.nih.gov/pubmed/21722250?tool=bestpractice.com. Ebola Virus Disease (EVD) is the international health emergency paradigm due to its epidemiological presentation pattern, impact on public health, resources necessary for its control, and need for a national and international response. Many of these symptoms are also present with other more common diseases, such as malaria and typhoid fever. Could Ebola virus be used for bioterrorism? Published online by Cambridge University Press: Ebola virus disease (EVD) is one of the most virulent pathogens among viral hemorrhagic fevers affecting economically deprived countries of the world with reported case fatality rates of up to 90% due to multi-organ failure and severe bleeding complications. For any urgent enquiries please contact our customer services team who are ready to help with any problems. The epidemic was a result of unsafe and unsanitary hospital practices, and non-sterilized medical equipment. Leroy EM, Gonzalez JP, Baize S. Ebola and Marburg haemorrhagic fever viruses: major scientific advances, but a relatively minor public health threat for Africa. Bats and rodents have been considered as potential reservoir species for a long time. Feb 2021 [internet publication]. 2020 Feb 20;6(1):13. doi: 10.1038/s41572-020-0147-3. doi: 10.1371/journal.pone.0179356. Recent outbreaks. Where a individual seeks care depends on the level of trust in the healthcare system, accessibility and abundance of healthcare facilities, financial and economic stance and cultural beliefs (WHO 2016). Bethesda, MD 20894, Web Policies In more effectively reporting suspected cases, Ebola response teams are better able to promptly follow-up, transfer to isolation centers, and assess the scope of the epidemic (Matua, Van der Wal, & Locsin. PLoS One. In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Ron Heeran, a speaker at the 2023 James L. Waters Symposium. Disease outbreak news: Ebola virus disease - Democratic Republic of the Congo. eCollection 2017. It was the third outbreak in the province in the last four years. Ebola virus disease Democratic Republic of the Congo. [31]World Health Organization. Ecologic and geographic distribution of filovirus disease. <> A man by the name of Thomas Eric Duncan boarded flight 822 from Liberia to Dallas, Texas. This virus was formerly known as the hemorrhagic fever. Advanced molecular detection and Liberian Ebola. Please note that medical information found World Health Organization. Please use one of the following formats to cite this article in your essay, paper or report: Metrovi, Tomislav. } Jun 2021 [internet publication]. and Read about the Epidemiologic Triangle. Zhang M, Wang X, Hu L, Zhang Y, Zheng H, Wu H, Wang J, Luo L, Xiao H, Qiao C, Li X, Huang W, Wang Y, Feng J, Chen G. Microbiol Spectr. https://www.who.int/emergencies/disease-outbreak-news/item/ebola-virus-disease-democratic-republic-of-the-congo-draft, 2018-2020: the worlds second largest outbreak in the north Kivu and Ituri provinces of the DRC in 2018 was declared over on June 25, 2020, with a total of 3481 cases and 2299 deaths (case fatality rate 66%). www.cidrap.umn.edu//commentary-health-workers-need-optimal-respiratory-protection-ebola "Being at first skeptical that Ebola virus could be an aerosol-transmissible disease, we are now persuaded by a review of experimental and epidemiologic data that this might be an important feature of disease transmission, particularly in healthcare settings.". With additional efforts and protocols instituted by organizations such as the Center for Disease Control and Prevention, the virus began to fall until the present day. Contrasting academic and lay press print coverage of the 2013-2016 Ebola Virus Disease outbreak. Mar 2020 [internet publication]. Early reports of Ebola virus disease from Guinea, CDC field team deployed. People at higher risk of infection include healthcare workers, family members or others who have close contact with infected people or who have contact with their bodies during funerals or burying rituals. In his spare time, Tomislav is a movie buff and an avid traveler. https://www.news-medical.net/health/Ebola-Virus-Epidemiology.aspx. These particular monoclonal antibodies bind to part of the Ebola viruss surface to prevent the virus from entering a persons cells. The ebola virus took the world by storm after it was carried to the United States and spread by people who had visited West Africa. If you have concerns about EVD, contact your healthcare provider. Avoid contact with semen from a man who had EVD until you know the virus is gone from the semen. Before <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> Ebola health update:north Kivu/Ituri, DRC, 2018-2020. https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON398, 2021: the thirteenth outbreak in the DRC started on October 8, 2021 in the North Kivu province and was declared over on December 16, 2021, with a total of 11 cases and 9 deaths (case fatality rate 82%). World Health Organization. World Health Organization. In 2014, a total of 20, 206 cases and 7,905 deaths were reported to have occurred in up to eight countries worldwide. Do ketogenic diets elevate low-density lipoprotein cholesterol levels? The Triangle has three. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395567/pdf/bullwho00439-0113.pdf The disease is introduced into the human population via close contact with the blood, bodily secretions, organs, or other fluids of infected animals. 2015 Jan;35(1):43-53. doi: 10.1002/phar.1545. Content may require purchase if you do not have access. MeSH Your feedback has been submitted successfully. 7t-P?xBwP%|byhU3F{7Ou6 `yl9]#| %P=mYRKQ>SZU,?z66.G\hT@w}vt*P -9AcJ"guP". 6TU*tV[Nw ~MqO\ !x0[".1@CIkeRq&g85Htl@(_%F 1$`(:6R.||w,(Q_N\`pn/ n (CGCM]/NT`Z`Dl''#m@J?IdC!Gk,2R@:IEgs1:bT S-4IkmYi)k4Ng4q>@MaQ$ stream (2) To the United States, there had never been any worry about the disease until September twentieth of 2014. World Health Organization. Ebola virus disease (EVD) in West Africa was first reported during early March 2014 in Guinea's 3 southeastern prefectures (Gueckedou, Macenta, and Kissidougou), which border Liberia and Sierra Leone; however, retrospective investigations indicate Ebola virus (EBOV) transmission might have occurred in Guinea since December 2013 (1-4).On March 27, 2014, EVD was reported in Conakry . Between March and May of 2014, the WHO sent more than 100 experts to aid in the control of the outbreak. Treatment for EVD also consists of supportive care and relief of symptoms. The site is secure. Contact Tracing: Barriers and Facilitators. Kavulikirwa, Olivier Kambere Careers. 1 0 obj There were many factors at play in this outbreak, such as the emergence of a new strain Ebola virus; a lack of preparedness in West. WHO recommended criteria for declaring the end of the Ebola virusdisease. News-Medical, viewed 01 May 2023, https://www.news-medical.net/health/Ebola-Virus-Epidemiology.aspx. [36]World Health Organization. This was the first outbreak caused bySudan ebolavirus in Uganda since 2012.[29]World Health Organization. "7b8= n4k7yRRQM>)/@I3X^s+}p-0+f9Gzw3MP:I&hRtqik pulo8jy@fia\evQ r8Xd`wf3tGB}OxCu,t^&V1VM/a'x(=O&)%kRYe8hCgU9Dq}! There is currently no FDA-licensed vaccine to protect against the three other strains of the Ebola virus that cause disease in people. Sikakulya, Franck Katembo 2021 May;25(10):4523-4533. doi: 10.1111/jcmm.16462. Keywords: burial practices, communicable disease, emerging disease, environment, epidemiology, infection, public health, risk exposure, surveillance, transmission, Suggested Citation: Aug 2022 [internet publication]. official website and that any information you provide is encrypted How many Ebola patients have been treated outside of Africa? VOV {Ki%/ ,*uP\u89c \Usr'2wUr{fYFypc(Lv+'TJg,8\fl~>I?lqh8;js3lIr=cBp@@j1M^OXp(' dXtlD`C 1G#?`O?rlXj`e< N Engl J Med. 2016 Aug 5;5(1):74. doi: 10.1186/s40249-016-0167-0. In addition to his interest in clinical, research and lecturing activities, his immense passion for medical writing and scientific communication goes back to his student days. A number of models of disease causation have been proposed. https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON433. Direct comparison of case fatality rates between different Ebola treatment centers and outbreaks should be interpreted with caution as many variables can introduce bias and skew even large cohort data. Ebola Epidemic: Student Worksheet Ebola Virus Disease (EVD), also known as Ebola hemorrhagic fever, is a rare and . Keywords: [34]World Health Organization. Although a considerable amount of effort has been put into identifying the natural reservoirs with every large outbreak of the disease, potential hosts or arthropod vectors for the Ebola virus have not been found. 2022 Dec;11(1):1635-1646. doi: 10.1080/22221751.2022.2086072. The presence of the Zaire ebolavirus in naturally infected fruit bats was first documented when viral RNA and antibodies were detected in three different bat species of the Pteropodidae family: Hypsignathus monstrosus, Epomops franqueti, and Myonycteris torquata. Disease outbreak news: Ebola virus disease - Democratic Republic of the Congo. The complex and unprecedented Ebola epidemic ongoing in West Africa has highlighted the need to review the epidemiological characteristics of Ebola Virus Disease (EVD) as well as our current understanding of the transmission dynamics and the effect of control interventions against Ebola transmission. Woolsey C, Fears AC, Borisevich V, Agans KN, Dobias NS, Prasad AN, Deer DJ, Geisbert JB, Fenton KA, Geisbert TW, Cross RW. stream Ebola virus disease (EVD) is one of the most virulent pathogens among viral hemorrhagic fevers affecting economically deprived countries of the world with reported case fatality rates of up to 90% due to multiorgan failure and severe bleeding complications. The evolution of Ebola virus disease outbreaks. Federal government websites often end in .gov or .mil. There is no FDA-authorized treatment for the three other strains of the Ebola virus that cause disease in people. Disease outbreak news. Ebola outbreaks with the Zaire and Ta Forest ebolaviruses have been observed in gorillas and chimpanzees since 1994. Ebola disease caused by Sudan ebolavirus Uganda. Jul 2022 [internet publication]. Disease outbreak news: Ebola virus disease - Democratic Republic of the Congo. xZn8} F p/L/vd1-DqloUQLSUbW`W|53Ug?HqP2! By clicking "Allow All" you agree to the storing of cookies on your device to enhance site navigation, The lack of IPC training lead to health care workers being 100 times more likely than the general population to contract Ebola (Ratnayake et al. Potluri R, Kumar A, Oriol-Mathieu V, Van Effelterre T, Metz L, Bhandari H. BMC Infect Dis. This article highlights the epidemiology, clinical features, diagnosis, management, and prevention of EVD. A directory of local health departments is located at, Visit the VDH website that contains information on Ebola virus disease at, Visit the Centers for Disease Control and Prevention website at. Ebola Virus Disease (EVD) is a virus transmitted from humans or animals through body fluids. In class we got a chance to discuss Ebola in the US and in Africa. jR06%oX^qTOHYs"F$+QI$G&Eem]Km^a*S3sFcz_ 1&. http://www.ncbi.nlm.nih.gov/pubmed/23285243?tool=bestpractice.com, 2022: an outbreak ofSudan ebolavirusdisease in Uganda started on September 20, 2022 and was declared over on January 11, 2023, with a total of 142 confirmed cases and 55 deaths (case fatality rate 39%). https://www.who.int/emergencies/disease-outbreak-news/item/2021-DON328, 2021: the twelfth outbreak in the DRC started on February 7, 2021 in the North Kivu province and was declared over on May 3, 2021, with a total of 12 cases and 6 deaths (case fatality rate 50%). Clipboard, Search History, and several other advanced features are temporarily unavailable. If EVD is suspected based on the persons symptoms and exposure to Ebola virus, such as having close contact with an Ebola-infected person, he or she should be isolated (separated from other people) immediately and the local health department should be notified. In terms of the reading in addition to the lecture by Haneefa Saleem, the class learned about what is the Ebola virus and its history, the affect it has on a person and their community in addition to how the world has perceived this virus. The case fatality rate during the 2014 outbreak was up to 64.3% in hospital admissions,[18]WHO Ebola Response Team. On March 25, 2014 the World Health Organization(WHO) announced the outbreak of a new strain of the Ebola virus disease with 86 suspected cases[15]. It is transmitted by means of contact with infected blood, mucous membranes, semen and other secretions, therefore being skin lesions and sexual contact significant ways of transmission (Boulton, 2014). 2011 Jul;17(7):964-76. Infection with the Ebola virus in Africa has occurred through the handling of infected gorillas, chimpanzees, monkeys, fruit bats, forest antelopes, and porcupines. 2022: an outbreak of Sudan ebolavirus disease in Uganda started on September 20, 2022 and was declared over on January 11, 2023, with a total of 142 confirmed cases and 55 deaths (case fatality rate 39%). Some observations have shown the decrease in case fatality ratio after several generations of patient-to-patient passage. Disease Outbreak News. This was the first outbreak in Guinea since the 2014-2016 West Africa outbreak. 1, 2 Due to its epidemiological presentation pattern, impact on public health, resources necessary for its management and control, as well as the need for a government site. Disease outbreak news. and transmitted securely. More info. There has been a change in the epidemiological profile of the Ebola outbreaks from 1976 through 2019 with an increase in the geographical extent of the outbreaks and the population at risk, as well as a significant decrease in the outbreaks case fatality rate. https://www.who.int/emergencies/situations/Ebola-2019-drc-, 2018: small outbreak in the DRC with 54 cases and 33 deaths (case fatality rate 61%).[2]World Health Organization. Study Objective: official website and that any information you provide is encrypted Ebola virus can spread to people when they have contact with an infected animals blood, body fluids, or tissues. Federal government websites often end in .gov or .mil. 2022: one case was reported in the DRC on August 21, 2022 in the North Kivu province. The Ebola-Zaire subtype is the most lethal variant. Spread to Nigeria and Senegal, CDC teams . Symptoms of EVD include fever, severe headache, muscle or joint pain, weakness, fatigue, sore throat, loss of appetite, diarrhea, vomiting, abdominal (stomach) pain, and, in some cases, unexplained hemorrhage (bleeding or bruising). January 2015 [internet publication]. The exact source of Ebola infections remains an open question, and despite all the efforts, there remains a lack of clear indicators about the reservoir of the virus. Is there an association between the consumption of ultra-processed food and adverse microbiota-gut-brain axis implications? May 2021 [internet publication]. The disease as it was discovered spread through direct contact of unmans to humans, and then thought, from non-human primates to humans. 1 0 obj Effective outbreak control requires a multidisciplinary team effort applying case management, infection prevention and control practices, surveillance and contact tracing, a good laboratory service, safe and dignified burials, and social and community mobilization. The virus obtained its name from the Ebola River in Africa. Genetic sequencing has shown that the virus isolated from infected patients in the 2014 outbreak is 97% similar to the virus that first emerged in 1976. Metrovi, Tomislav. However, bats are frequent residents in equatorial Africa, where they are even hunted for food. Feb 2021 [internet publication]. About three hundred people in each of the two nations were infected with the virus, resulting in a mortality rate of 88% in Zaire, and 53% in Sudan (Bulletin of the WHO 1978). Design a strategy to contain the Ebola outbreak. Annu Rev Virol. How can I learn more about Ebola virus disease? Be sure the info you fill in Epidemiologic Triangle For Ebola is updated and correct. MeSH United States Agency for International Development, United Nations Office for Project Services, Office for the Coordination of Humanitarian Affairs, UN Mission for Ebola Emergency Response (UNMEER). Suggested Citation, Maidan Garhischool of social sciencesNew Delhi, 110068India, Subscribe to this fee journal for more curated articles on this topic, International Institutions: Transnational Networks eJournal, Political Economy - Development: Health eJournal, We use cookies to help provide and enhance our service and tailor content. 2022. https://www.nytimes.com/interactive/2014/07/31/world/africa/ebola-virus-outbreak-qa.html, In contrast to this, the Sudan ebolavirus has a lower case fatality rate of 39% to 65% in previous outbreaks, with the largest outbreak occurring in 2000 in Uganda (425 cases). Nov 2020[internet publication]. The most common species of Ebola virus responsible for outbreaks is the Zaire ebolavirus, the second most common species being the Sudan ebolavirus. When healthcare workers became infected colleges became frightened further reducing community trust in the healthcare system. Each genus includes some serotypes with the distinctive characteristics to cause high mortality rate during outbreaks. Those vertices are "agent," "host," and "environment." Jacob ST, Crozier I, Fischer WA 2nd, Hewlett A, Kraft CS, Vega MA, Soka MJ, Wahl V, Griffiths A, Bollinger L, Kuhn JH. Moreover, the outbursts have appeared in Africa over the following 27 years, with death rates that differ from 50 to 90%. hasContentIssue false, World Association for Disaster and Emergency Medicine 2020. 2022. Ebola haemorrhagic fever in Zaire, 1976. 18 March 2020. World Health Organization. As the Ebola virus in the reservoir might present in a subclinical or asymptomatic way, there is a possibility of sporadic activation via appropriate stimuli such as stress, changes in food patterns, or infection with other pathogens, which has been demonstrated in experimental conditions. The virus is transmitted to people from wild animals and spreads in the human population through human-to-human transmission. Emerg Microbes Infect. A study conducted in Liberia in 2014 proved such hypothesis to be true and concluded that prompt and accurate isolation of infected patients was a safe method. 01 May 2023. The triad consists of an external agent, a susceptible host, and an environment that brings the host and agent together.

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