Tissues were processed automatically using automatic tissue processor (Leica TP 1020) and allowed to pass through varying percentage of alcohol and absolute alcohol for the purpose of dehydration following dewaxing in Xylene for 15mins. J Acute Disease. 2016;4(1):5360. Article The reaction is terminated by the addition of 2ml of dichromoacetic acid mixture (potassium dichromate (5%) and glacial acetic acid; 1:3v/v) and heated at 60C for 10min. Although, medically, it is advised you see your doctor or a physician before using the leaf for medicinal uses. Ewe eje is safe and healthy for consumption. The description of these plants has been written based on numerous outside resources. Growing up, we were told many biblical stories, Negro pepper (Xylopia aethiopica) is a spice plant that possess several health benefits, which make it an indispensable, Eating for its sour taste when fairly ripen and sweet taste when well ripen, star apple finds favor, Fertility tree (Newbouldia laevis), also known as boundary tree, Ogirisi in Igbo, Adikuru in Hausa and Ewe akoko, Guava (Psidium guajava) is a well known tropical tree which is widely grown for its fruits. Sci. 1. This could possibly indicate SOD stimulating effects of J. carnea leaf ethanol extract. The renal cortex showed normal glomeruli with mesangial cells and capsular spaces appeared normal (white arrow), the renal tubules appear normal (blue arrow) and interstitial spaces also observed normal (black arrow). Lorke D. A new approach to practical acute toxicity testing. Kone WM, Koffi AG, Bomisso EL, Tra Bi FH. List of various diseases cured by Justicia Betonica. 5. 1958;25(1):192205. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. Saunders; 1995. p. 26873. Oyenihi OR, Brooks NL, Oguntibeju OO. These minerals help in boosting blood production, which is why the plant is called ogwu obara (blood medicine) among the Igbo people of Southern Nigeria. Powdered sample was extracted using absolute ethanol and concentrated to obtain a slurry paste of J. carnea ethanol extracts. Infertility after therapy, in particular, imposes a significant mental strain on young patients. Manage cookies/Do not sell my data we use in the preference centre. The renal effects of blood glucose-lowering plant-derived extracts in diabetes mellitus-an overview. Cite this article. Elevated activity of catalase in liver and kidney across tested doses of J. carnea ethanol extract showed no significant effect compared to the control. The Health benefit of Ewe eje (Justicia carnea leaf) are highlighted in this article. Clin Phytosci 2019; 5:9. https://doi.org/10.1186/s40816-019-0104-4. It is an awesome plant and worth your time and attention. Methods. Article ID 687197, 2013; p. 13. https://doi.org/10.1155/2013/687197. Except the group that received 1200mg/kg JCEE which showed significant (p<0.05) elevation of SOD and MDA in the liver, other doses (<1200mg/kg) demonstrated no significant difference compared to the control. 10.17306/J.AFS.2017.0492. From this study, the significant increase in platelet counts suggested that the extract could be useful in preventing excessive blood loss (through blood clotting) and resistance of capillary membranes to leakage of red cells when blood vessels are damaged. Great for use as a foundation or mass planting, it is also terrific for containers or as a houseplant. Despite the therapeutic importance of medicinal plants, toxic substances have been shown to be present in large numbers of plants investigated [3]. Justicia carnea (belonging to Acanthaceae family) is a flowering plant consisting ~600 species that are widely distributed in the tropics and subtropics [7]. J Ethnopharmacol. International Journal of Phytomedicine and Phytotherapy, Clinical Phytoscience Authors TSO, KOK and ESA manage experimental protocols and performed the experiments under the supervision of FOA. Mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) showed significant (p<0.05) increased at 50mg/kg while doses greater than 100mg/kg showed no significant difference compared to the control. Therapeutic Research Faculty 2020. Rats were further observed for extended hours of 48h to see if mortality would occur. Author ESA managed the literature searches and wrote the first draft of the manuscript with the assistant of FOA. Note: A=change in absorbance, TV=total volume, SV=sample volume, TP=total protein, =molar extinction =1.34104M1 cm1. Locklear, T. D., Huang, Y., Frasor, J., Doyle, B. J., Perez, A., Gomez-Laurito, J., and Mahady, G. B. Estrogenic and progestagenic effects of extracts of Justicia pectoralis Jacq., an herbal medicine from Costa Rica used for the treatment of menopause and PMS. Tropical habitats mean constant moisture. Becoming a contributing member of Gardenia is easy and can be done in just a few minutes. Sun M, Zigma S. An improved spectrophotometer assay of superoxide dismutase based on epinephrine autoxidation. It is not. The flowering Justicia plant is a perennial native to the Atlantic Forest eco-regions in eastern Brazil. MacRae, W. D. and Towers, G. H. Justicia pectoralis: a study of the basis for its use as a hallucinogenic snuff ingredient. Despite living in close proximity to this plant, many individuals may be unaware of its benefits. The resultant liquid would turn crimson red. 2004;19(12):16. Chariandy, C. M., Seaforth, C. E., Phelps, R. H., Pollard, G. V., and Khambay, B. P. Screening of medicinal plants from Trinidad and Tobago for antimicrobial and insecticidal properties. Stover PJ, Caudill MA. The animals were initially examined for any signs of toxicity after 60min of administration and further observed for a period of 24h. The absence of rat mortality in phase I necessitated the conduct of the second phase. Ethanol extract of J. carnea leaf elevated red blood cell, hemoglobin, packed cell volume and platelet count with significant increase at higher doses of extracts compared to the control. Walters DM., Cho Hye-Youn, Kleeberger SR. Oxidative Stress and Antioxidants in the Pathogenesis of Pulmonary Fibrosis: A Potential Role for Nrf2. How to make Ewe eje Extracthow to prepare justicia carnea. It has been shown also that other specie of justicia improve central nervous system functions and health and protect it from toxic damages. Niger J Physiol Sci. The leaves of justicia carnea possess high content of iron and vitamin C. This compounds may be responsible for the blood boosting property of ewe eje leaves. I do hope that after reading through this article, you would plan to start cultivating this amazing plant specie in your garden. CAS When the Jacobinians are newly planted, water them daily for a few weeks. Joseph, H., Gleye, J., Moulis, C., Mensah, L. J., Roussakis, C., and Gratas, C. Justicidin B, a cytotoxic principle from Justicia pectoralis. It may be, judging from the antidepressant activity of other plant of justicia species whose activity have been studied, proper to state that justicia carnea may possess antidepressant properties. It creates the perfect environment for aphids and dried sod. Inhibitory Potential and Antidiabetic Activity of Leaf Extracts of Justicia carnea. To create additional collections, you must be a paid member of our site. Onyeabo C, Achi NK, Ekeleme-Egedigwe CA, Ebere CU, Okoro CK. Phytochemical profile, antioxidant, -amylase inhibition, binding However, serious caution of the dose should be taken into consideration when extrapolating this result for human consumption. However, coadministration of both extracts exerts a synergistic effecton the . Justicia carnea - Wikipedia Adetuyi is a Professor of Biochemistry in the Department of Chemical Sciences, Faculty of Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. The results of this study suggests that ethanol extract of J. carnea leaf is relatively safe, could be beneficial in alleviating hematology related abnormalities without causing adverse effects on endogenous antioxidant system. The cuttings are taken from the parent plant in the spring after the plant has bloomed. Haematological and biochemical studies on Justicia carnea leave extract in phenylhydrazine induced-anemia in albino rats. Local consumers of the leaves are mostly . However, the mechanism by which phytochemicals act as prooxidants in-vivo is still under investigation [25]. Occupational Health and Safety in the Care and Use of Research Animals. In which ever condition, the blood glucose level increases abnormally. Pot the specimen and bring it indoors to add a bright touch of color to your interiors. Part shade is the ideal growing condition for Brazilian plumes. It also grows in some Caribbean islands, including Trinidad and Tobago . Hepatoprotective Effect of Methanol Extract of Justicia carnea Leaves It also increases good cholesterol levels. Nutritive properties of aqueous extract Justicia carnea leaves and its effects on haematological and some biochemical indices of anaemia induced male wistar albino rats. This lends the plant some interesting names such as Blood of Jesus plant and Hospital too far. Lipid peroxidation was determined by measuring the formation of thiobarbituric acid reactive substances (TBARS) according to the method described by Buege and Aust [20]. J Ethnopharmacol. Absorbance reading was taken at 620nm regularly at an interval of 1min against reagent blank. The significant decrease in kidney GSH at 1200mg/kg could be due to ample dietary bioactive constituents in the extract that requires frequent conjugation of GSH in the cell or oxidation to oxidized glutathione (GSSG). Although the antidepressant activity of justicia carnea has not been studied, and so may be hard to prove its efficacy scientifically, the leaves of justicia carnea have been used in traditional medicine to treat depression and anxiety disorder. Pinch out tips to promote compact plants. Therefore,it is imperative to investigate the effects of the plant on the essential biochemical indices in diabetic rats so as to establish its safety. Over time, they cause atherosclerosis and myocardia infarction. At this time there is not enough scientific information to determine an appropriate range of doses for Justicia pectoralis. The Justicia carnea leaves are rich in B-vitamins. One of the health benefits of justicia carnea is in boosting immune system. Treatments of all experimental animals were performed following Principle of Laboratory Animal Care manual guidebook of National Institute of Health as approved by the Research Ethics Committee of Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State. In recent time, copious attention has been focused on the use of medicinal plants in the management and treatment of ailments such as anemia, diabetes and malaria. Compared to the control, total protein in liver and kidney were statistically not altered except rats that were administered with 1200mg/kg JCEE that showed significant (p<0.05) decrease in the liver. Wash the Justicia carnea leaves thoroughly to eliminate all forms of insects and dust. Contamination of medicinal plant could be as a result of contaminants (such as heavy metals, aflatoxin and pathogenic microbes) from soil and manner of herbal preparations [4]. The genus Justicia named after the 18th-century Scottish botanist James Justice is a flowering plant in the family Acanthaceae. No observable focal sclerosis of renal glomeruli, capsular spaces around the glomerulus appears normal with distinct layering of renal microcellular structures. Gas chromatography/mass spectrometry of simple coumarins, 3-phenylpropionic acids and their hydroxy and methoxy derivatives. Fresh leaves of Justicia carnea were collected from Okitipupa area Ondo State. J Ethnopharmacol. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. de Smet, P. A. Justicia pectoralis might have many different effects in the body. The findings back up local assertions that they can be. Acta Scientiarum Polonorum, Technologia Alimentaria. Mapanga RF, Musabayane CT. Justicia carnea has been used in traditional medicine to treat diabetes. Excitedly, scientific studies have supported the traditional claims. It is commonly referred to as blood root, blood booster, ewe eje in Yoruba, Ogwu obara in Igbo, and jacobinia in Brazil and south America. 2007;112(1):13844. 2016;5(1):6270 https://doi.org/10.1016/j.joad.2015.08.006. While histology of organs showed no adverse pathological lesions in the internal organs of rats, higher dose (1200mg/kg) over a period of time could cause noticeable liver and kidney injury. Molecules (Basel, Switzerland), 19(12), 2144221461. Uses, Benefits, Cures, Side Effects, Nutrients in Justicia Betonica. It has been reported previously that under certain conditions, dietary antioxidants such as ascorbic acid, tocopherol and carotenoids could act, occasionally, as pro-oxidants to initiate slight degree of oxidative stress microenvironment. Decreased white blood cell count was obtained in this report, the level of lymphocyte and granulocyte was not altered by the extract while MID sized cell was significantly elevated at 500 and 800mg/kg dose. The LD50 of extract was greater than 5000mg/kg body weight. View abstract. Organic extract of Justicia pectoralis Jacq. This plant is somewhat drought-tolerant once established but looks best with regular watering during periods of extended dry weather. Star Apple: Amazing Health Benefits of eating its fruits. The animals were randomly distributed into cages and allowed to acclimatize for 2 weeks in a well ventilated room under natural lighting condition.
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